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Is your health suffering from a folic acid deficiency?
Folic acid occurs naturally as a complex of related substances called folates, found in sprouts, Brewers' yeast, liver and kidney.
However, levels are soon diminished following cooking and processing. And since most of us do not consume enough folate-rich foods, experts believe that many of us are suffering from a folic acid deficiency.

Furthermore, studies in healthy human participants show that folic acid is poorly absorbed from the diet anyway, which results in very little of the metabolically active form, methylfolate, being produced.

Folic acid undergoes a series of complicated vitamin and energy-dependent changes in your body, between your intestine and liver, before it is converted to its active form, methylfolate. A break in any one of these processes resulting from dietary deficiency, malabsorption and genetic weaknesses can soon lead to low levels of methylfolate in your brain. Now, new research suggests that neurological symptoms such as memory loss, sleep issues, irritability, forgetfulness, and mood issues may result.

Neurobiologix specializes in many products that contain forms of Folate, Folinic Acid and 5-Methyltetrahydrofolate. Most often, those that are poor methylators will need additional folate in some form.

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Bioactive B12-Folate 60T / Retail $25.90 Bioactive B12-Folate 60T / Retail $25.90

High-potency, fast-dissolving tablets.

Bioactive B12-Folate® combines the active coenzyme form of vitamin B12, methylcobalamin, with an active form of folate, Metafolin®* L-5-methyltetrahydrofolate. This high-potency, bioactive formula was created to bypass normal absorptive mechanisms for vitamin B12 and folate which may be impaired due to aging, illness, gastrointestinal issues or a methylation deficiency.


Fast-dissolving and great tasting tablets allow for quick release into the bloodstream. Vitamin B12 and folate play an integral role in DNA synthesis and thus are essential to cell division and proper functioning of virtually all tissues in the body. Vitamin B12 and folate also participate in methylation and proper metabolism of homocysteine, a potentially toxic metabolite of methionine.

Dietary B12 can be reliably obtained only from animal products and is a singularly difficult vitamin to absorb. Bioactive B12-Folate may be especially beneficial for vegetarians and persons with impaired gastrointestinal absorptive function due to aging, illness, surgery or a methylation deficiency.


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Methyl Folate Plus Methyl Folate Plus - 90 Capsules (Retail $37.90)


Improved Formula Now With 30mg Vitamin B2 (Riboflavin-5-Phosphate)
and Niacinamide For Cofactor Delivery

This formula is an optimal methylation formula with activating co-factor created by Kendal Stewart, MD to support the methylation pathway and provide adequate folinic acid and methyl folate (5-MTHF).

This product is designed to be used in conjunction with the Methylation Complete Fast Dissolves OR Methylation Pro Topical that provides the activating B12 co-factors to deliver the additional tetrahydrofolate to support neurological and immune recovery. For those who have high folic acid levels in the blood plasma, then it can be assumed that folate is not being converted and entering the nervous sytem, immune system and blood brain barrier. Most often poor methylators will need additional folate.

The addition of Niacinamide helps support the mitochondria and supports as a cofactor for the delivery of the other ingredients in Methyl Folate Plus.

Dr. Stewart lecture: The Methyl Folate Deficiency.

The typical indications for this product include but are not limited to:

* Presence of Folate Receptor Autoantibodies

*Homozygous (2 copies) MTHFR polymorphism

*Increased requirement for development (age 8-20)

*Acute recovery from major neurological injuries

*Moderate to severe autism related issues

*Poor recovery from surgery or injury


Dr. Stewart Discusses Methyl Folate Plus and It's Use for Neuro-Immune Syndromes from Neurobiologix on Vimeo.


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Methylation Complete Sublingual 120T (Retail $53.90) Methylation Complete Sublingual 120T (Retail $53.90)


2 Forms of Bioactive B12 (Methylcobalamin / Hydroxycobalamin) , B6 (P-5-P) and Methyl Folate (5-Methyltetrahydrofolate)
Ultimate Methylation Support and Dissolves In Under 60 Seconds!

Our unique sublingual delivery system assures that our pharmaceutical grade Methylation Complete™ promotes and enhances the methylation processes needed to improve the production of glutathione, and allow maximum B12, B6 and 5-Methyltetrahydrofolate delivery to the nervous and immune systems. This sublingual may help maximize and aid in:
  • Mood Improvement & Stabilization
  • Mental Focus & Concentration
  • Organization Skills
  • MTHFR / MTRR Mutations
  • Short Term Memory
  • Cerebral Folate Deficiency
  • Hormonal Regulation
  • Sleep Patterns
  • Immune Function

Methylation Complete Sublingual Product Video with Dr. Kendal Stewart from Neurobiologix on Vimeo.


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Methylation Complete Sublingual TRAVEL SIZE 10t (Retail $5.25) Methylation Complete Sublingual TRAVEL SIZE 10t (Retail $5.25)

TRAVEL SIZE OPTION - 10 tablets per bottle

2 Forms of Bioactive B12 (Methylcobalamin/Hydroxycobalamin) , B6 (P-5-P) and Methyl Folate
Ultimate Methylation Support and Dissolves In Under 60 Seconds!

Our unique sublingual delivery system assures that our pharmaceutical grade Methylation Complete™ promotes and enhances the methylation processes needed to improve the production of glutathione, and allow maximum B12, B6 and 5-Methyltetrahydrofolate delivery to the nervous and immune systems. This sublingual may help maximize and aid in:
  • Mood Improvement & Stabilization
  • Mental Focus & Concentration
  • Organization Skills
  • MTHFR / MTRR Mutations
  • Short Term Memory
  • Cerebral Folate Deficiency
  • Hormonal Regulation
  • Sleep Patterns
  • Immune Function

Methylation Complete Sublingual Product Video with Dr. Kendal Stewart from Neurobiologix on Vimeo.


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Methylation Pro Topical 2oz. (Retail $55.90) NEW! Methylation Pro Topical 2oz. (Retail $55.90) NEW!

NEW!
Enhanced Formula With Additional 5-Methyltetrahydrofolate (5-MTHF) and Now Vitamin K For Improved Delivery

Advanced Topical Cream for Neurological, Nervous & Immune System Support / Ultimate Methylation Support

The addition of Vitamin K in this methylation suppport cream is recommended for those who are hindered by a methylation deficiency and/or a VDR Taq genetic polymorphism which inhibits the person's ability to absorb vitamin D at the cellular level without the cofactor Vitamin K. Impaired vitamin D function due to this polymorphism can result in significant immune weakness, early bone loss and increased risk of cognitive decline and mood issues.

As a solution, our unique topical delivery system, assures that our pharmaceutical grade Neuro-Immune Stabilizer Creamª promotes and enhances the methylation processes needed to improve the production of glutathione, increase Vitamin D levels and allow maximum B12, B6 and vitamin delivery to the nervous and immune systems. This potent nutrient-rich cream may help maximize and aid in:

  • Mood Improvement & Stabilization
  • Mental Focus & Concentration
  • Organization Skills
  • MTHFR Mutations
  • Short Term Memory Loss
  • Supporting a healthy sleep cycle
  • Immune Function and well-being
  • Patients with a VDR Taq mutation (SNP)
Such nutrients as Pyridoxal 5-Phosphate (B6) and Vitamin B12 in a methylated form called methylcobalamin (Methyl B12) and hydroxycobalamin (Hydroxy B12) and natural Vitamin D and K assist the body neurologically and physically.

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neuro methylation cream Neuro-Immune Stabilizer Topical Cream (120 pumps) / (Retail $55.90)

Now Available! Enhanced Formula With Additional 5-Methyltetrahydrofolate (5-MTHF) and Improved Delivery System!
Topical Cream for Neurological, Nervous & Immune System Support

As a solution, our unique topical delivery system, assures that our pharmaceutical grade Neuro-Immune Stabilizer Cream promotes and enhances the methylation processes needed to improve the production of glutathione, increase Vitamin D levels and allow maximum B12, B6 and vitamin delivery to the nervous and immune systems. This potent nutrient-rich cream can help maximize and aid in:
  • Mood Improvement & Stabilization
  • Mental Focus & Concentration
  • Organization Skills
  • 5 MTHR Mutation
  • Short Term Memory Loss
  • Cerebral Folate Deficiency
  • Hormonal Regulation
  • Sleep Patterns
  • Immune Function
Active Ingredients: 5-Methyltetrahydrofolate (5-MTHF), Methyl B12, Hydroxy B12, Pyridoxal 5-Phosphate (B6) and 1,000 IU's Vitamin D per pump.



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5-MTHF: The Best Form Of Folate Supplementation

In the body, the folate molecule goes through several enzymatic steps to become the active molecule 5-MTHF. It is the active 5-MTHF form of folate that participates in the homocysteine-lowering step that results in the production of the safe amino acid, methionine which is essential to cellular function.

In theory, supplementing with folic acid—the most common form of folate in supplement form—should provide the body with the folate it needs to convert dangerous homocysteine into safe methionine. Unfortunately, this readily available homocysteine-lowering regimen doesn’t work for everyone.

That’s because in order to make the conversion from folate to the active 5-MTHF, an enzyme called methylenetetrahydrofolate reductase or MTHFR is necessary—and not everyone carries the same genetic version of this important enzyme. It is estimated that between 5 and 10% of the population has a gene variant that reduces MTHFR activity by 70%, while nearly 50% of people of European descent have a genetic variation that decreases MTHFR activity by as much as 35%.

If you fall into these categories, you are likely to be a victim of methylation deficiencies that can cause numerous issues with the nervous or immune system.

The solution is simple: Instead of relying only on the folic acid in your multinutrient formula, supplement with 5-MTHF.

A wealth of laboratory and human studies demonstrate that 5-MTHF is the best form of folate required.

The conversion process diagram below guides you through the steps the body must take in order to convert folic acid or folate to the active form 5-Methyltetrahydrofolate which is essential to every cell in the body. At Neurobiologix we start with the active form of folate so your body does not have to go through the process of conversion.